Results for Point Mutation
Search for mutation:
- by receptor: hTSHR
- at position: 505
Highlight result values
| Functional parameter | in red below [%] | in green above [%] |
|---|
Results
| Substructure | No | Ba-We | wildtype | mutant | binding | expression | Gs_basal activation | Gs_max stimulation | Gq_basal activation | Gq_max stimulation | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| TMH3 | 505 | 3.36 | Ser | Asn | details | 78 | - | 490 | 103 | - | - |
| TMH3 | 505 | 3.36 | Ser | Asn | details | - | 80 | 650 | 109 | 88 | 100 |
| TMH3 | 505 | 3.36 | Ser | Arg | details | - | 60 | 275 | 92 | - | - |
| TMH3 | 505 | 3.36 | Ser | Arg | details | 93 | - | 218 | 100 | 109 | 50 |
| TMH3 | 505 | 3.36 | Ser | Arg | details | - | - | 250 | - | - | - |