Results for Point Mutation
Search for mutation:
- by receptor: hTSHR
- at position: 572
Highlight result values
| Functional parameter | in red below [%] | in green above [%] |
|---|
Results
| Substructure | No | Ba-We | wildtype | mutant | expression | Gs_basal activation | Gs_max stimulation | Gq_basal activation | Gq_max stimulation | |
|---|---|---|---|---|---|---|---|---|---|---|
| ECL2 | 572 | Met | Ala | details | 81 | 20 | 57 | 100 | 14 | |
| ECL2 | 572 | Met | Ala | details | 86 | 80 | 48 | - | - | |
| ECL2 | 572 | Met | Phe | details | 93 | 120 | 58 | 133 | 70 |