Results for Point Mutation
Search for mutation:
- by receptor: hTSHR
- at position: 573
Highlight result values
| Functional parameter | in red below [%] | in green above [%] |
|---|
Results
| Substructure | No | Ba-We | wildtype | mutant | binding | expression | Gs_basal activation | Gs_max stimulation | Gq_basal activation | Gq_max stimulation | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ECL2 | 573 | Asp | Ala | details | - | 65 | 130 | 74 | 94 | 68 | |
| ECL2 | 573 | Asp | Lys | details | 40 | 32 | 50 | 79 | 140 | 12 |