Glycoprotein Hormone Receptors - TSHR, FSHR, LHCGR (LHR)
Sequence-Structure-Function-Analysis
of Glycoprotein Hormone Receptors
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last updated: 2017-01-17
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Results for Point Mutation
Search for mutation:
by receptor: rLHCGR
at position: 284
Highlight result values
Functional parameter
in red below [%]
in green above [%]
binding
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expression
Update
Gs_max stimulation
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Results
rLHCGR
UniProtKB/Swiss-Prot
3d model
Substructure
No
Ba-We
wildtype
mutant
binding
expression
Gs_max stimulation
LRR11
284
Cys
Ala
details
-
0
0
LRR11
284
Cys
Ser
details
0
-
-
Mutation details
Details for rLHCGR at position 284 mutation Ala
Parameter
Celltype
Ligand
Value [% wt]
Comment
Publication
expression
HEK-293
0
Zeng H, Phang T, Son...
Gs_max stimulation
HEK-293
humCG
0
Zeng H, Phang T, Son...
Corresponding Mutations of homologous receptors
Receptor
Wildtype
Position
Ba-We
hTSHR
Cys
284
details
hLHCGR
Cys
280
details
Mutation details
Details for rLHCGR at position 284 mutation Ser
Parameter
Celltype
Ligand
Value [% wt]
Comment
Publication
binding
COS-1
humCG
0
results as diagram
Zhang R, Buczko E, D...
Corresponding Mutations of homologous receptors
Receptor
Wildtype
Position
Ba-We
hTSHR
Cys
284
details
hLHCGR
Cys
280
details
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first release: 2005-08-25