Results for Point Mutation
Search for mutation:
- by receptor: hFSHR
- at position: 449
Highlight result values
| Functional parameter | in red below [%] | in green above [%] |
|---|
Results
| Substructure | No | Ba-We | wildtype | mutant | binding | expression | Gs_basal activation | Gs_max stimulation | |
|---|---|---|---|---|---|---|---|---|---|
| TMH3 | 449 | 3.32 | Thr | Ala | details | - | 190 | 280 | - |
| TMH3 | 449 | 3.32 | Thr | Ala | details | - | 256 | 250 | 150 |
| TMH3 | 449 | 3.32 | Thr | Asp | details | - | 114 | 104 | 120 |
| TMH3 | 449 | 3.32 | Thr | Phe | details | - | 227 | 975 | 139 |
| TMH3 | 449 | 3.32 | Thr | Gly | details | - | 232 | 290 | 140 |
| TMH3 | 449 | 3.32 | Thr | Ile | details | 70 | 98 | 100 | 87 |
| TMH3 | 449 | 3.32 | Thr | Ile | details | - | 200 | 536 | 152 |
| TMH3 | 449 | 3.32 | Thr | Asn | details | - | 140 | 150 | 95 |
| TMH3 | 449 | 3.32 | Thr | Arg | details | - | 206 | 136 | 0 |
| TMH3 | 449 | 3.32 | Thr | Ser | details | - | 160 | 114 | 95 |
| TMH3 | 449 | 3.32 | Thr | Tyr | details | - | 285 | 425 | 117 |