Glycoprotein Hormone Receptors - TSHR, FSHR, LHCGR (LHR)
Sequence-Structure-Function-Analysis
of Glycoprotein Hormone Receptors
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last updated: 2013-03-22
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Results for Point Mutation
Search for mutation:
by receptor: hFSHR
at position: 53
Highlight result values
Functional parameter
in red below [%]
in green above [%]
binding
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expression
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Gs_max stimulation
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Results
hFSHR
UniProtKB/Swiss-Prot
3d model
Substructure
No
Ba-We
wildtype
mutant
binding
expression
Gs_max stimulation
LRR2
53
Phe
Ala
details
0
-
-
LRR2
53
Phe
Ala
details
-
0
0
Mutation details
Details for hFSHR at position 53 mutation Ala
Parameter
Celltype
Ligand
Value [% wt]
Comment
Publication
binding
HEK293
humFSH
0
Ji I, Lee C, Jeoung ...
Corresponding Mutations of homologous receptors
Receptor
Wildtype
Position
Ba-We
hLHCGR
Leu
56
details
Mutation details
Details for hFSHR at position 53 mutation Ala
Parameter
Celltype
Ligand
Value [% wt]
Comment
Publication
expression
HEK-293
0
Song YS, Ji I, Beauc...
Gs_max stimulation
HEK-293
humFSH
0
Song YS, Ji I, Beauc...
Corresponding Mutations of homologous receptors
Receptor
Wildtype
Position
Ba-We
hLHCGR
Leu
56
details
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first release: 2005-08-25