AF6/ERBIN PDZ domain - Selectivity below 100 micro-molar

Recognized by the AF6 and ERBIN PDZ domains

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P3 P2 P1 P0 Seq. AF6-Kd ERBIN-Kd SNA1-Kd
E I F V EIFV 9.20 63.87 135.94
E V F V EVFV 11.96 43.52 129.18
E W W V EWWV 19.02 79.06 118.45
S V W V SVWV 19.16 84.92 140.65
D I W V DIWV 27.38 57.20 222.44
E V W I EVWI 30.79 92.88 113.07
D V F V DVFV 31.71 81.58 375.58
D V W V DVWV 35.61 38.98 211.38
V V W V VVWV 40.93 87.17 136.15
T V W V TVWV 41.28 97.67 224.50
E A F V EAFV 44.61 99.71 125.51
E Y W V EYWV 45.26 87.19 116.09
E M W V EMWV 60.36 81.67 105.67
D V W L DVWL 97.84 99.43 268.20

Reference:
Urs Wiedemann and Prisca Boisguerin, Rainer Leben, Dietmar Leitner, Gerd Krause, Karin Moelling, Rudolf Volkmer-Engert and Hartmut Oschkinat (2004) submitted.


Last modified: Sun May 02 19:10:07 W. Europe Daylight Time 2004

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