AF6 PDZ domain - Selectivity below 10 micro-molar

Exclusively recognized by AF6 PDZ domain

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P3 P2 P1 P0 Seq. AF6-Kd ERBIN-Kd SNA1-Kd
G I F V GIFV 6.97 325.84 667.18
A I F V AIFV 7.53 347.56 347.20
G I W V GIWV 7.83 155.69 375.49
A I W V AIWV 8.45 166.06 195.40
G V F V GVFV 9.07 222.05 634.01
G F F V GFFV 9.12 604.56 813.12
E I F V EIFV 9.20 63.87 135.94
G T F V GTFV 9.22 71.09 91.78
A V F V AVFV 9.79 236.85 329.94
A F F V AFFV 9.84 644.86 423.14
A T F V ATFV 9.95 75.83 47.76

Reference:
Urs Wiedemann and Prisca Boisguerin, Rainer Leben, Dietmar Leitner, Gerd Krause, Karin Moelling, Rudolf Volkmer-Engert and Hartmut Oschkinat (2004) submitted.


Last modified: Sun May 02 19:10:43 W. Europe Daylight Time 2004

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