ERBIN/SNA1 PDZ domain - Selectivity below 50 micro-molar

Recognized by the ERBIN and SNA1 PDZ domains

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P3 P2 P1 P0 Seq. AF6-Kd ERBIN-Kd SNA1-Kd
E T D V ETDV 65.75 19.34 10.13
E T A V ETAV 108.70 20.53 8.19
D S W V DSWV 63.34 23.80 29.70
E T S V ETSV 63.37 24.89 9.41
E T N V ETNV 57.80 28.89 8.84
D T W L DTWL 99.52 31.83 38.82
E S W L ESWL 65.65 32.39 12.96
I T W V ITWV 52.36 32.52 33.55
E T Q V ETQV 62.60 33.81 9.78
E T R V ETRV 80.49 34.19 7.30
E T P V ETPV 96.06 36.10 16.40
D T D V DTDV 174.29 36.26 29.45
E S D V ESDV 114.98 36.89 9.83
D T A V DTAV 288.15 38.48 23.80
E S A V ESAV 190.09 39.15 7.94
E T H V ETHV 79.87 39.20 11.76
E T M V ETMV 70.02 42.52 11.79
M T W V MTWV 63.93 43.11 23.80
N T W V NTWV 53.43 44.93 28.86
E T E V ETEV 59.45 45.09 8.79
D T S V DTSV 167.98 46.65 27.36
E S S V ESSV 110.81 47.47 9.13
E T D L ETDL 180.66 49.34 12.85

Reference:
Urs Wiedemann and Prisca Boisguerin, Rainer Leben, Dietmar Leitner, Gerd Krause, Karin Moelling, Rudolf Volkmer-Engert and Hartmut Oschkinat (2004) submitted.


Last modified: Sun May 02 19:15:20 W. Europe Daylight Time 2004

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