SNA1 PDZ domain - Selectivity below 10 micro-molar

Exclusively recognized by SNA1 PDZ domain

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P3 P2 P1 P0 Seq. AF6-Kd ERBIN-Kd SNA1-Kd
E S T V ESTV 74.75 117.29 5.95
E T T V ETTV 42.75 61.50 6.13
E S V V ESVV 62.93 231.67 6.33
E T V V ETVV 35.99 121.48 6.52
E S R V ESRV 140.75 65.20 7.09
E T R V ETRV 80.49 34.19 7.30
E S T L ESTL 205.40 299.18 7.55
E T T L ETTL 117.46 156.88 7.78
E S A V ESAV 190.09 39.15 7.94
E S V L ESVL 172.91 590.97 8.03
E T A V ETAV 108.70 20.53 8.19
E T V L ETVL 98.88 309.89 8.27
E S K V ESKV 253.23 109.14 8.50
E S E V ESEV 103.96 85.98 8.53
E S N V ESNV 101.08 55.09 8.58
E S I V ESIV 61.19 292.21 8.66
E T K V ETKV 144.81 57.23 8.76
E T E V ETEV 59.45 45.09 8.79
E T N V ETNV 57.80 28.89 8.84
E T I V ETIV 34.99 153.23 8.92
E S R L ESRL 386.74 166.31 8.99
E S S V ESSV 110.81 47.47 9.13
E S T I ESTI 171.34 523.85 9.26
E T R L ETRL 221.16 87.21 9.26
E T S V ETSV 63.37 24.89 9.41
E S Q V ESQV 109.47 64.47 9.49
E T T I ETTI 97.98 274.69 9.54
E T Q V ETQV 62.60 33.81 9.78
E S D V ESDV 114.98 36.89 9.83
E S V I ESVI 144.24 1034.76 9.84

Reference:
Urs Wiedemann and Prisca Boisguerin, Rainer Leben, Dietmar Leitner, Gerd Krause, Karin Moelling, Rudolf Volkmer-Engert and Hartmut Oschkinat (2004) submitted.


Last modified: Sun May 02 19:15:47 W. Europe Daylight Time 2004

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