Sequence-Structure-Function-Analysis

Fox KM, Dias JA, Van Roey P
Three-dimensional structure of human follicle-stimulating hormone
Mol Endocrinol. 2001 Mar;15(3):378-89
PDB: 1FL7

Tegoni M, Spinelli S, Verhoeyen M, Davis P, Cambillau C
Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits
J Mol Biol. 1999 Jun 25;289(5):1375-85
PDB: 1QFW

Lapthorn AJ, Harris DC, Littlejohn A, Lustbader JW, Canfield RE, Machin KJ, Morgan FJ, Isaacs NW
Crystal structure of human chorionic gonadotropin
Nature. 1994 Jun 9;369(6480):455-61
PDB: 1HRP

Standfuss, J., Xie, G., Edwards, P.C., Burghammer, M., Oprian, D.D., Schertler, G.F.
Crystal Structure of a Thermally Stable Rhodopsin Mutant.
J.Mol.Biol. v372 pp. 1179, 2007
PDB: 2J4Y

Salom, D., Lodowski, D.T., Stenkamp, R.E., Trong, I.L., Golczak, M., Jastrzebska, B., Harris, T., Ballesteros, J.A., Palczewski, K
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa v103 pp. 16123-16128, 2006
PDB: 2I35

Okada T, Sugihara M, Bondar AN, Elstner M, Entel P, Buss V
The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure
J Mol Biol. 2004 Sep 10;342(2):571-83
PDB: 1U19

Li J, Edwards PC, Burghammer M, Villa C, Schertler GF
Structure of bovine rhodopsin in a trigonal crystal form
J Mol Biol. 2004 Nov 5;343(5):1409-38
PDB: 1GZM

Teller, D.C., Okada, T., Behnke, C.A., Palczewski, K., Stenkamp, R.E.
Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
Biochemistry v40 pp. 7761-7772, 2001
PDB: 1HZX

Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M
Crystal structure of rhodopsin: A G protein-coupled receptor
Science. 2000 Aug 4;289(5480):739-45
PDB: 1F88

Rasmussen, S.G., Choi, H.J., Rosenbaum, D.M., Kobilka, T.S., Thian, F.S., Edwards, P.C., Burghammer, M., Ratnala, V.R., Sanishvili, R., Fischetti, R.F., Schertler, G.F., Weis, W.I., Kobilka, B.K.
Crystal structure of the human beta(2) adrenergic G-protein-coupled receptor.
Nature, 2007
PDB: 2R4R

Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G., Thian, F.S., Kobilka, T.S., Choi, H.J., Kuhn, P., Weis, W.I., Kobilka, B.K., Stevens, R.C.
High-Resolution Crystal Structure of an Engineered Human {beta}2-Adrenergic G Protein Coupled Receptor.
Science, 2007
PDB: 2RH1

Warne, A., Serrano-Vega, M.J., Baker, J.G., Moukhametzianov, R., Edwards, P.C., Henderson, R., Leslie, A.G.W., Tate, C.G., Schertler, G.F.X.
Structure of the Beta1-Adrenergic G Protein-Coupled Receptor
(2008) Nature 454: 486
PDB: 2VT4

Jaakola, V.P., Griffith, M.T., Hanson, M.A., Cherezov, V., Chien, E.Y., Lane, J.R., Ijzerman, A.P., Stevens, R.C.
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
(2008) Science 322: 1211-1217
PDB: 3EML

Scheerer, P., Park, J.H., Hildebrand, P.W., Kim, Y.J., Krauss, N., Choe, H.-W., Hofmann, K.P., Ernst, O.P.
Crystal structure of opsin in its G-protein-interacting conformation
(2008) Nature 455: 497-502
PDB: 3DQB

Park, J.H., Scheerer, P., Hofmann, K.P., Choe, H.-W., Ernst, O.P.
Crystal structure of the ligand-free G-protein-coupled receptor opsin
(2008) Nature 454: 183-187
PDB: 3CAP

Sanders, J., Chirgadze, D.Y., Sanders, P., Baker, S., Sullivan, A., Bhardwaja, A., Bolton, J., Reeve, M., Nakatake, N., Evans, M., Richards, T., Powell, M., Miguel, R.N., Blundell, T.L., Furmaniak, J., Smith, B.R.
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Thyroid. 2007 May;17(5):395-410.
PDB: 3G04

Fan QR, Hendrickson WA
Structure of human follicle-stimulating hormone in complex with its receptor
Nature. 2005 Jan 20;433(7023):203-4
PDB: 1XWD

Sunahara, R. K., Tesmer, J. J., Gilman, A. G., Sprang, S. R.
Crystal structure of the adenylyl cyclase activator Gsalpha
Science 278 pp. 1943 (1997)
PDB: 1AZT

Wall, M. A., Coleman, D. E., Lee, E., Iniguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., Sprang, S. R.
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2
Cell 83 pp. 1047 (1995)
PDB: 1GP2

Wall, M. A., Coleman, D. E., Lee, E., Iniguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., Sprang, S. R.
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2
Cell 83 pp. 1047 (1995)
PDB: 1GG2